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KiloSportsIsoleucine

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Description: Typical Analysis:
L-Isoleucine is a free-form essential amino acid supplement.  Isoleucine is an essential amino acid because it must be obtained directly from the diet as it is not produced by the body.  Isoleucine is a branched chain amino acid, along with leucine and valine.  Together they make up approximately 70 percent of the total amino acids in the body.  As such they are crucial to the structural integrity of the body.
Appearance: White crystalline powder
Specific Rotation: (@20o C) +40.9
Ammonia (NH4): 0.020%
Chloride (CL): 0.021%
Sulfate (SO4): 0.028%
Iron (FE): 20 ppm
Heavy Metals (PB): 10 ppm
Arsenic (As2O3): 1 ppm
Homogeneity: Pass
Test By PPC (50mcg)    
Loss on drying: 0.05% Color
Residue on ignition: 0.02%
Purity (dry basis): 100%
Pharmacology:
Branched chain amino acids help stimulate muscle protein synthesis, so they are valuable for body-building as a sport, and also for preventing muscle wasting and helping with healing after surgery or trauma.  Their decomposition products can be used by the body to create branched fatty acids, which can become part of complex phospholipids.  Isoleucine can be converted to sugar in the liver, so it can help maintain blood glucose levels.  Also it is used to build hemoglobin, which carries iron in the blood.
Directions: Toxicity:
200 to 2000 mg per day, with plenty of liquid, on an empty stomach at least an hour before meals, or at bedtime.  This is because other protein in a meal will block absorption of this amino acid. Avoid if subject to "maple syrup urine disease."  Otherwise safe for human and animal use.  For best results, do not take with protein meal.
  Studies:
  Young, V.R., et al.; Recent developments in knowledge of human amino acid requirements.  Nitrogen Metabolism in Man, eds: J.C.

Waterlow & J.M.L. Stephen, London: Applied Science Publishers, 1981. 

Morgan, M.Y. et al.; Plasma ratio of valine, leucine and isoleucine to phenylalanine and tyrosine in liver disease. Gut, vol. 19: 1068-1073, 1978. 

Amino Acids\Isoleucine, in The Natural Health Information System TM, available from Health Info Systems, 408-479-0227; 1501 Adrian Road, Burlingame, CA 94010.


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